| Start | End | Session | Location |
|---|---|---|---|
| 08:30 | 10:00 | Saga Hall | |
| Moderators: | John O’Shea, National Institutes of Health | ||
| Ewa Sitnicka, Lund University | |||
| 08:30 | |||
| Andreas Diefenbach, Charité Berlin | |||
| Innate lymphoid cells and tissue remodeling | |||
| 08:50 | |||
| Barbara Kee, University of Chicago | |||
| ETS all about NK cells and innate lymphocytes | |||
| 09:10 | |||
| Joseph Sun, Memorial Sloan Kettering Cancer Center | |||
| Fasting reshapes tissue-specific NK cell immunity | |||
| 09:30 | |||
| Sebastian Scheer, Luxembourg Institute of Health | |||
| The methyltransferase DOT1L controls NK cell activation and lineage integrity. | |||
| 09:40 | |||
| Stephanie Jost, Duke University | |||
| Adaptive NK cells responses against antigenically distinct influenza viruses are partly mediated by HLA-E-stabilizing peptides derived from conserved antigens | |||
| 09:50 | |||
| Everardo Hegewisch-Solloa, Columbia University Irving Medical Center | |||
| A multifaceted deep dive into the NK cell developmental niche within human secondary lymphoid tissue. | |||
| 10:00 | 10:30 | Coffee Break | Foyer |
| 10:30 | 12:00 | Saga Hall | |
| Moderators: | Michael Caligiuri, City of Hope National Medical Center | ||
| Cynthia Dunbar, National Institutes of Health | |||
| 10:30 | |||
| Nicolas Serafini, Institut Pasteur | |||
| Intestinal ILC3: Better, Faster, Stronger | |||
| 10:50 | |||
| Chiara Romagnani, Charité University and DRFZ Berlin | |||
| Dynamics of human NK cell memory and clonality | |||
| 11:10 | |||
| Yenan Bryceson, Karolinska Institutet | |||
| To be announced | |||
| 11:30 | |||
| Helena Arellano Ballestero, University College London | |||
| Tumour-priming induces memory-like properties on NK cells: characterisation of the proteomic and receptor profile | |||
| 11:40 | |||
| Ming Cheng, University of Science and Technology of China | |||
| Transcription factor ROR-alpha promotes the formation and long-term maintenance of memory ILC1s | |||
| 11:50 | |||
| Markus Uhrberg, Heinrich-Heine University Düsseldorf | |||
| A novel human NK cell progenitor that originates in the thymus and generates NKG2A-KIR+ NK cells | |||
| 12:00 | 13:30 | Lunch | Restaurant |
| 13:30 | 15:00 | Saga Hall | |
| Moderators: | Dimitra Peppa, University College London | ||
| Quirin Hammer, Karolinska Institutet | |||
| 13:30 | |||
| Mariapia Degli-Eposti, Monash University | |||
| To be announced | |||
| 13:50 | |||
| Catherine Blish, Stanford University | |||
| Interrogating human coronavirus escape from and susceptibility to NK cell killing | |||
| 14:10 | |||
| Stephen Waggoner, Cincinnati Children's Hospital Medical Center | |||
| Using forensic victimology and immunological gun control to stop a follicular murder | |||
| 14:30 | |||
| Simon Grassman, Memorial Sloan Kettering Cancer Center | |||
| Early antigen-receptor signaling primes NK cells for optimal cytokine signaling during infection | |||
| 14:40 | |||
| Jesse Bruijnesteijn, Biomedical Primate Research Centre | |||
| Chromosomal rearrangements in the KIR gene cluster as evolutionary strategy to fight fast evolving pathogens | |||
| 14:50 | |||
| Wilfredo Garcia-Beltran, Ragon Institute of Mass General, MIT and Harvard | |||
| SARS-CoV-2 evades NK-cell immunity by ORF6-mediated shedding of NKG2D ligands, uncovering a novel immunotherapeutic target conserved among sarbecoviruses | |||
| 15:00 | 15:30 | Coffee Break | Foyer |
| 15:30 | 16:40 | Saga Hall | |
| Moderators: | Marcus Altfeld, Leibniz Institute for Virology | ||
| Clair Gardiner, Trinity College Dublin | |||
| 15:30 | |||
| Mary Carrington, Frederick National Laboratory for Cancer Research | |||
| Impact of HLA class I Signal Peptide Variation on HLA-E interactions with CD94/NKG2A | |||
| 15:50 | |||
| Marit Inngjerdingen, University of Oslo | |||
| Unravelling the heterogeneity of extracellular vesicles released from NK cells | |||
| 16:10 | |||
| Patrick Ross, San Diego Biomedical Research Institute | |||
| Leveraging MINFLUX Nanoscopy to Understand NK Cell Immunological Synapse Structure and Dynamics | |||
| 16:20 | |||
| Anzelika Rubina, Cardiff University | |||
| Human cytomegalovirus genes UL148 and UL148D inhibit NK cell function by promoting surface expression of inhibitory ligands via impairment of ADAM17 | |||
| 16:30 | |||
| Jean De Lima , University of Basel | |||
| Redefining the lung immune cell network: crosstalkbetween HIF-1a+ CD4 T cells and NK cells during influenza infection | |||
| 16:40 | 17:10 | Saga Hall | |
| Moderators: | Amir Horowitz, Mount Sinai | ||
| Janine Melsen, Leiden University Medical Center | |||
| 16:40 | |||
| Giovanna Perinetti Casoni, Karolinska Institutet | |||
| DEF6 promotes canonical CD56dim NK cell survival and cytotoxicity | |||
| 16:45 | |||
| Adriana Mujal, Memorial Sloan Kettering Cancer Center | |||
| Tissue-specific determinants of adaptive NK cell responses | |||
| 16:50 | |||
| Tomas Hofman, Heidelberg University | |||
| IFNg- and sialic acid pathways drive melanoma resistance via selective inhibition of NK cell subsets. | |||
| 16:55 | |||
| Nicole Wild, Karolinska Institutet | |||
| Characterisation of organ-specific tissue-resident NK cells across human tissues | |||
| 17:00 | |||
| Janine Melsen, Leiden University Medical Center | |||
| Deciphering human NK cell development using high-dimensional phenotyping and imaging: tonsil versus thymus | |||
| 17:05 | |||
| Roseanna Hare, University of Manchester | |||
| Ligand mobility is necessary for TIGIT to assemble into nanoscale clusters at immune synapses | |||
| 17:30 | 20:00 | Visit to Fram museum [Ticket Required] | Fram |
| 20:00 | 21:30 | Poster Sesson 2, B001-B131 | Poster Area |
